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Chemical Engineering

Biomedical Engineering

Biomedical engineering involves the application of engineering principles to understand, modify or control biological systems with the objective of generating solutions to health-related problems. This area is diverse and multi-disciplinary, bringing in concepts from chemistry, mechanics, biochemistry, cell biology and physiology.

Research efforts in this field at Queen's include the development of polymer biomaterials for use as implantable drug delivery devices and scaffolds for regenerative medicine and tissue engineering, biosensor development, and microencapsulation technologies for drug delivery. This work involves collaboration with researchers in many other Departments such as: the Divisions of Orthopedic and Cardiovascular Surgery, the Department of Biomedical and Molecular Sciences, and the Department of Mechanical and Materials Engineering. In addition, many projects involve both cardiovascular and orthopaedic surgeons. Much of the research is done within the Human Mobility Research Centre.

Students enrolled in a graduate program in Chemical Engineering may apply for an interdisciplinary program in biomedical engineering. Upon graduation, students will have "with specialization in Biomedical Engineering" added to their academic record. Visit the Collaborative Biomedical Engineering page for more details.

Meet Laura McKiel, a graduate student in Biomedical Engineering at Queen’s:

Laura McKiel, PhD Candidate, Chemical Engineering from Queen's Engineering on Vimeo.

Research Terminology

Polymer Biomaterials

Polymers represent an exciting and rapidly developing area of biomaterials, with a wide range of possible applications. Here at Queen's, Dr. Amsden is developing biodegradable photocrosslinkable elastomers and hydrogels as implantable growth factor delivery devices and as scaffolds for the regeneration of soft tissues such as articular cartilage and the intervertebral disc, low melt viscosity biodegradable polymers for local growth factor delivery, and biodegradable crimped microfibres as scaffolds for ligament tissue engineering.

crimped fibres in vivo elastomer porous scaffold trichrome
crimped biodegradable microfibres in vivo degradation of biodegradable elastomer porous scaffold made of biodegradable elastomer tissue response to elastomer implantation

Tissue Engineering and Regenerative Medicine

Through tissue engineering and regenerative medicine, investigators seek to create novel tissue substitutes that will integrate into the body, promoting regeneration and restoring function to damaged tissues or organs. Extensive research is being conducted at Queen's to develop tissue-engineering strategies for a range of soft tissue applications. Dr. Amsden is developing new polymer materials for drug delivery and as scaffolds for the treatment of damaged articular cartilage and the intervertebral disc, as well as on the development of a tissue engineered ligament. Dr. Waldman's research focuses on connective tissues, including tissue engineering functional articular cartilage and intervertebral disc. Dr. Flynn is investigating multipotent mesenchymal stem cells derived from human fat in naturally derived scaffolds, to create novel constructs to promote soft tissue regeneration in reconstructive applications. Many of these projects are also collaborative with research direction provided by each faculty member.

TEM waldman PAS HE tissue fibres

Research Faculty

Names

Rank

Contact

Research Interests


Brian Amsden

Professor

 brian.amsden@queensu.ca
  BioSci 1422A
  (613) 533-3093

Polymer biomaterials, Protein drug delivery, Tissue engineering, Controlled release, Diffusion in gels and polymer solutions


Lindsay Fitzpatrick

Assistant Professor 

 lindsay.fitzpatrick@queensu.ca 
 Dup 302
 (613) 533-6000 ext 78936

Biomedical engineering, focusing on identifying the molecular mechanisms that govern the initiation and resolution of inflammation in the presence of biomaterials, and using this knowledge to develop advanced materials for chronic wound therapies


Laura Wells

Assistant
Professor 

 laura.wells@queensu.ca
 BioSci 4628
 (613)-533-6000 ext 75836

Biomedical engineering, focusing on the development of new types of polymeric materials for drug delivery and tissue engineering in wound healing and ophthalmic applications. She is particularly interested in cell/material interactions, and plans to develop strategies for designing and synthesizing polymers that respond to biological and physical stimuli


Kim Woodhouse

Professor

 dean@appsci.queensu.ca
 Beamish-Munro 200
 (613) 533-2056

Tissue engineering, polymer biomaterials