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Chemical Engineering

CHEE440

CHEE440 : Pharmaceutical Technology

Personnel

Instructor

Laura WellsDupuis 301laura.wells@queensu.ca613-533-6000 x 75836

TAs

Course Description

Introduction to pharmaceutics and the industrial manufacture of pharmaceutical dosage forms. Topics include the design and preparation of a successful dosage form with respect to the route of administration, and large scale manufacture in a sterile and clean environment. Aspects of chemical kinetics, physical chemistry, physiology, cell biology, mass and heat transfer, and fluid dynamics will be described as they relate to the manufacture of effective dosage forms. (0/12/0/30/0)

Objectives and Outcomes

The objective of this course is to provide the students with an understanding of the application of mathematics, physical chemistry and engineering unit operations in the manufacture and assessment of basic dosage forms. 

Specific course learning outcomes include: 

  1. Explain the physiological routes of absorption for drugs and the advantages and limitations of each route.
  2. Describe and mathematically analyze the absorption, distribution, and elimination of drugs from various dosage forms.
  3. Analyze and solve problems involving unit operations in the context of the design and manufacture of tablets, capsules, solutions, suspensions and emulsions.
  4. Describe the ethics, safety and regulatory standards around manufacture and regulatory approval of pharmaceutical products.

This course develops the following attribute:

Knowledge base

CHEE-KB-BIO-2. Applies foundations of science, materials science, and engineering in biological, physiological, pharmaceutical and/or environmental problems or processes.                           

Relevance to the Program

This elective course, offered at the 4th year level, applies foundations of mathematics, science, and engineering in the pharmaceutical setting and provides bio/physiological insight for biomedical engineering applications.  

Course Structure and Activities

3 lecture hours and 1 tutorial hour per week.  Times and locations can be found on SOLUS. 

Resources

Recommended Textbook: The Design and Manufacture of Medicines, Michael E. Aulton & Kevin M.G. Taylor, 4th Edition.

All course lecture slides, assignments and tutorials will be posted on online in the course learning management system (LMS).