Chemical Engineering


CHEE452 : Transport Phenomena in Physiological Systems



Brian AmsdenBioSci 1422amsden@queensu.ca613-533-3093


Saeed Rizmani YazdiDUP 23912sry@queensu.ca

Course Description

This course is an introduction to the area of mass, momentum and heat transfer processes in physiological systems. In this course the student will appreciate the role of transport phenomena in the function of organs and organ systems in the body, and develop the skills necessary to analyze models of biological transport processes in the context of the design of biomedical devices. (0/0/0/42/0)

PREREQUISITES:  CHEE 223 and CHEE 330, or permission of the department


Objectives and Outcomes

This course provides an overview of transport phenomena in biological systems that are critical to the function of all living organisms. The fundamental laws and equations of transport phenomena will be applied to topics including cellular, cardiovascular, respiratory, liver and kidney transport, blood flow and rheology, and circulation in tissues and arteries. The course objectives are to:

  1. Describe the roles of heat, mass and momentum transfer in the function of physiological processes
  2. Analyze and solve problems involving heat, mass, and momentum transfer in the body in the context of the design and application of biomedical devices for the treatment of injury and disease.

Specific course learning outcomes include:

  1. Identify transport properties and analyze the mechanisms of molecular momentum, energy and mass transport.
  2. Select, locate and orient coordinate systems for transport phenomena problems (including rectangular and curvilinear).
  3. Formulate the differential forms of the equations of change for momentum, heat and mass transfer problems for steady-state and unsteady flows.
  4. Create original solutions to fluid flow, heat transfer and mass transfer problems
  5. Develop original solutions to fluid flow in compliant systems
  6. Create original solutions to combined fluid flow and heat transfer, heat and mass transfer and fluid flow and mass transfer problems
  7. Recognize non-Newtonian liquids and apply appropriate models to describe them
  8. Understand and appreciate physiology of the cardiovascular system and how it can be modeled.

This course assesses the following attributes:

Knowledge base (CLO 1-6): Analyzes transport of fluids (viscous fluid flow) in closed conduits and external flows CHEE-KB-FM-4; formulates and solves differential equations of heat transfer to calculate temperature distributions CHEE-KB-HT-2; Solves problems involving convective heat transfer using appropriate correlations CHEE-KB-HT-3; Formulates and solves differential equations of mass transfer to calculate concentration distributions CHEE-KB-MT-2; Solves problems involving convective mass transfer using appropriate correlations CHEE-KB-MT-3; Applies foundations of science, materials science, and engineering in biological, physiological, pharmaceutical and/or environmental problems or processes. CHEE-KB-BIO-2.

Relevance to the Program

This course applies knowledge developed in the prior transport courses  CHEE 223, CHEE 224 and CHEE 330 to problems that deal with physiological systems.  This course complements and expands knowledge developed in CHEE 340, Biomedical Engineering, and equips the students who follow the Biochemical Engineering option with knowledge that is essential in the understanding of transport processes in biological systems.

Course Structure and Activities

3 lecture hours + 1 tutorial hour per week.  Please check SOLUS for times and locations


Recommended Textbook:  Roselli and Diller, Biotransport: Principles and Applications

Other useful resource: Transport phenomena in biological systems, George A. Truskey, Fan Yuan, David F. Katz, 2004. On hold in the E&S Library.

All course lecture slides, assignments and tutorials will be posted on online on the LMS.